LYZL4

Across TCGA patient cohorts, LYZL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,837 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LYZL4-associated GO terms across cancer lineages are Vacuolar acidification, Phosphatidylethanolamine metabolic process, and Depyrimidination. Each is linked with LYZL4 in more than 9 cancer types. Because this analysis shows association rather than direction, both LYZL4-to-partner and partner-to-LYZL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar acidification grouped by LYZL4-low versus LYZL4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL4→partner) and Y-score (partner→LYZL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Vacuolar acidification →	+0.055	+0.176	<.001	.001	3	10
KIRC	Phosphatidylethanolamine metabolic process →	+0.046	+0.043	<.001	<.001	2	10
KIRC	Depyrimidination →	+0.057	+0.049	<.001	<.001	3	9
STAD	Glycerolipid biosynthetic process →	+0.040	+0.114	<.001	<.001	3	9
KIRC	Phosphatidylcholine biosynthetic process →	+0.046	+0.043	<.001	<.001	3	9
STAD	Positive regulation of cell growth →	+0.047	+0.209	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,837 associations by consensus.

Vacuolar acidification by LYZL4 expression — STAD

Explore this box plot interactively →