LYZL4

Across TCGA cell cohorts, LYZL4 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LYZL4-associated genes across cancer lineages are ELOA3DP, OR13G1, and OR6Q1. Each is linked with LYZL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYZL4-to-partner and partner-to-LYZL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by LYZL4-low versus LYZL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL4→partner) and Y-score (partner→LYZL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.023	+4.273	.003	.006	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR6Q1 →	+0.022	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ELOA3DP by LYZL4 expression — LARGE_INTESTINE

Explore this box plot interactively →