LYZL4

Across TCGA cell cohorts, LYZL4 mutation is significantly associated with the mutation status of many other genes, with 1,121 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LYZL4-associated genes across cancer lineages are ZNF667, CP, and BICRA. Each is linked with LYZL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both LYZL4-to-partner and partner-to-LYZL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF667 grouped by LYZL4-low versus LYZL4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL4→partner) and Y-score (partner→LYZL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ZNF667 →	+4.392	+4.392	.009	.009	1	3
SKIN	CP →	+4.392	+4.392	.009	.009	1	2
SKIN	BICRA →	+3.169	+4.548	.004	.004	1	2
SKIN	ATP2C2 →	+3.655	+4.906	.001	.001	1	2
SKIN	SNAP91 →	+2.977	+4.392	.005	.005	1	2
SKIN	PHTF2 →	+4.392	+5.357	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,121 associations by consensus.

ZNF667 by LYZL4 expression — SKIN

Explore this box plot interactively →