LYZL2

Across TCGA patient cohorts, LYZL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,577 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LYZL2-associated GO terms across cancer lineages are Regulation of protein localization to chromosome, telomeric region, Positive regulation of cell cycle G2/M phase transition, and Regulation of cyclin-dependent protein kinase activity. Each is linked with LYZL2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LYZL2-to-partner and partner-to-LYZL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to chromosome, telomeric region grouped by LYZL2-low versus LYZL2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL2→partner) and Y-score (partner→LYZL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein localization to chromosome, telomeric region →	+0.079	+0.133	<.001	<.001	3	8
STAD	Positive regulation of cell cycle G2/M phase transition →	+0.066	+0.133	<.001	<.001	3	8
STAD	Regulation of cyclin-dependent protein kinase activity →	+0.064	+0.127	<.001	<.001	3	8
STAD	Positive regulation of telomere capping →	+0.064	+0.122	<.001	<.001	3	8
STAD	Ubiquinone metabolic process →	+0.064	+0.123	<.001	<.001	3	7
STAD	Telomerase RNA localization →	+0.067	+0.112	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,577 associations by consensus.

Regulation of protein localization to chromosome, telomeric region by LYZL2 expression — STAD

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