LYZL2

Across TCGA cell cohorts, LYZL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 618 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LYZL2-associated GO terms across cancer lineages are Positive regulation of calcium ion transport into cytosol, Positive regulation of triglyceride storage, and Microglia development. Each is linked with LYZL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LYZL2-to-partner and partner-to-LYZL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of calcium ion transport into cytosol grouped by LYZL2-low versus LYZL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL2→partner) and Y-score (partner→LYZL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of calcium ion transport into cytosol →	-0.216	-0.598	<.001	.001	3	2
BREAST	Positive regulation of triglyceride storage →	-0.178	-0.445	.001	.003	3	2
BREAST	Microglia development →	+0.158	+0.692	<.001	<.001	3	2
BREAST	Coenzyme A transport →	+0.079	+0.516	.001	<.001	3	2
BREAST	Regulation of hemostasis →	-0.121	-0.525	.002	.007	3	2
BREAST	Regulation of hyaluranon cable assembly →	+0.967	+0.661	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 618 associations by consensus.

Positive regulation of calcium ion transport into cytosol by LYZL2 expression — BREAST

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