LYVE1

Across TCGA cell cohorts, LYVE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 642 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible LYVE1-associated GO terms across cancer lineages are Wound healing, Negative regulation of neuron apoptotic process, and Cellular response to type I interferon. Each is linked with LYVE1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LYVE1-to-partner and partner-to-LYVE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by LYVE1-low versus LYVE1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYVE1→partner) and Y-score (partner→LYVE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Wound healing →	+0.094	+0.040	<.001	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of neuron apoptotic process →	+0.051	+0.025	<.001	.007	2	6
BLOOD_Lymphoma	Cellular response to type I interferon →	+0.098	+0.013	<.001	.005	3	5
LUNG_NSCLC_LUAD	Maintenance of protein localization in organelle →	+0.058	+0.016	.004	.002	3	5
UPPER_AERODIGESTIVE_TRACT	Intracellular receptor signaling pathway →	+0.046	+0.019	<.001	.003	3	4
UPPER_AERODIGESTIVE_TRACT	Negative regulation of protein catabolic process →	+0.056	+0.029	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

Wound healing by LYVE1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →