LYVE1

Across TCGA cell cohorts, LYVE1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LYVE1-associated genes across cancer lineages are OR10A6 and CFHR2. Each is linked with LYVE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYVE1-to-partner and partner-to-LYVE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A6 grouped by LYVE1-low versus LYVE1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYVE1→partner) and Y-score (partner→LYVE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CFHR2 →	+0.395	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10A6 by LYVE1 expression — BLOOD_Leukemia

Explore this box plot interactively →