LYST

Across TCGA patient cohorts, LYST RNA expression is significantly associated with the protein abundance of many other proteins, with 10,008 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LYST-associated proteins across cancer lineages are AIDA, MYO1G, and ARHGEF1. Each is linked with LYST in more than 5 cancer types. Because this analysis shows association rather than direction, both LYST-to-partner and partner-to-LYST results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYST versus AIDA in PDAC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYST→partner) and Y-score (partner→LYST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AIDA →	+0.305	+0.319	<.001	.001	3	6
LUAD	MYO1G →	+0.428	+0.493	<.001	<.001	3	4
COAD	ARHGEF1 →	+0.218	+0.407	.002	.002	3	4
BRCA	RSL1D1 →	-0.423	-0.586	<.001	<.001	3	4
BRCA	WDR43 →	-0.312	-0.689	<.001	<.001	3	4
LUAD	RPL5 →	-0.208	-0.553	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,008 associations by consensus.

LYST vs AIDA — PDAC

Explore this scatter interactively →