LYSMD4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LYSMD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYSMD4-associated proteins across cancer lineages are P4HB, FNDC3B_S208, and HDLBP. Each is linked with LYSMD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYSMD4-to-partner and partner-to-LYSMD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYSMD4 versus P4HB in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYSMD4→partner) and Y-score (partner→LYSMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMP4HB →-0.542-0.381<.001<.00135
LUADFNDC3B_S208 →-0.467-0.424<.001.00135
LSCCHDLBP →-0.267-0.444<.001<.00135
LSCCPPP1R18_S145 →-0.502-0.520.001.00134
GBMNNMT →-0.794-0.359.003<.00134
GBMRCN1 →-0.431-0.354<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,360 associations by consensus.

LYSMD4 vs P4HB — GBM

Per-sample scatter of LYSMD4 vs P4HB in GBM (Pearson r = -0.39).

Explore this scatter interactively →

Exploration