LYSMD4

Across TCGA cell cohorts, LYSMD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,632 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LYSMD4-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with LYSMD4 in more than 11 cancer types. Because this analysis shows association rather than direction, both LYSMD4-to-partner and partner-to-LYSMD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by LYSMD4-low versus LYSMD4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYSMD4→partner) and Y-score (partner→LYSMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.139	+1.001	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.115	+1.002	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.142	+0.924	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.112	+0.908	<.001	<.001	3	10
BREAST	Regulation of myoblast fusion →	+0.087	+0.544	.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.079	+0.693	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,632 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by LYSMD4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →