LYSMD3

Across TCGA patient cohorts, LYSMD3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,321 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYSMD3-associated genes across cancer lineages are UCK2, DHX35, and CEP76. Each is linked with LYSMD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LYSMD3-to-partner and partner-to-LYSMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYSMD3 versus UCK2 in LUAD, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYSMD3→partner) and Y-score (partner→LYSMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UCK2 →	-0.746	-0.284	<.001	<.001	3	4
LSCC	DHX35 →	-0.545	-0.206	<.001	<.001	3	3
LSCC	CEP76 →	-0.564	-0.214	<.001	<.001	3	3
LSCC	NFYA →	-0.653	-0.282	<.001	<.001	3	3
LSCC	GTF3C3 →	-0.448	-0.169	<.001	<.001	3	3
BRCA	NCAPH →	-0.680	-0.321	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,321 associations by consensus.

LYSMD3 vs UCK2 — LUAD

Explore this scatter interactively →