Across TCGA patient cohorts, LYRM7 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,600 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LYRM7-associated proteins across cancer lineages are MRE11, CKAP4_S26, and PMVK. Each is linked with LYRM7 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYRM7-to-partner and partner-to-LYRM7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM7→partner) and Y-score (partner→LYRM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRE11 →	+0.428	+0.607	<.001	<.001	3	5
BRCA	CKAP4_S26 →	-0.889	-0.459	<.001	<.001	3	5
PDAC	PMVK →	+0.403	+0.296	<.001	<.001	3	5
BRCA	RRBP1 →	-0.481	-0.478	<.001	<.001	3	5
OV	HSPA4 →	+0.301	+0.500	<.001	<.001	3	5
OV	KDM3B →	+0.354	+0.604	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,600 associations by consensus.

Exploration

LYRM7 survival (RNA) · tumor vs normal (RNA) · all LYRM7 data types