Across TCGA patient cohorts, LYRM7 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYRM7-associated genes across cancer lineages are CSTP2, RNU6-1290P, and RNA5SP507. Each is linked with LYRM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYRM7-to-partner and partner-to-LYRM7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM7→partner) and Y-score (partner→LYRM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CSTP2 →	+0.267	+3.638	<.001	.001	3	1
UCEC	RNU6-1290P →	+0.358	+4.464	<.001	.005	3	1
UCEC	RNA5SP507 →	+0.668	+2.940	<.001	.007	3	1
UCEC	RNA5SP455 →	+0.375	+4.885	<.001	.002	3	1
UCEC	RNU6-937P →	+0.588	+2.815	.001	.008	3	1
UCEC	SNORA10B →	+0.274	+3.294	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

LYRM7 survival (RNA) · tumor vs normal (RNA) · all LYRM7 data types