Across TCGA patient cohorts, LYRM4 mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYRM4-associated genes across cancer lineages are TAAR5, NUTF2P8, and NTAN1P1. Each is linked with LYRM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYRM4-to-partner and partner-to-LYRM4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM4→partner) and Y-score (partner→LYRM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAAR5 →	+0.215	+2.448	.001	.008	3	2
UCEC	NUTF2P8 →	+0.156	+3.398	<.001	.001	3	1
UCEC	NTAN1P1 →	+0.119	+4.352	.001	<.001	3	1
UCEC	RNVU1-28 →	+0.778	+2.857	.001	.002	3	1
UCEC	KIR3DL1 →	+0.266	+3.910	.001	.001	3	1
UCEC	FAM172BP →	+0.360	+3.518	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

Exploration

LYRM4 survival (RNA) · tumor vs normal (RNA) · all LYRM4 data types