LYRM2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LYRM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,319 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYRM2-associated proteins across cancer lineages are AFDN, SYNCRIP, and VTA1. Each is linked with LYRM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYRM2-to-partner and partner-to-LYRM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYRM2 versus AFDN in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM2→partner) and Y-score (partner→LYRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAAFDN →+0.397+0.371.003.00535
OVSYNCRIP →+0.394+0.475<.001.00235
GBMVTA1 →+0.242+0.344<.001<.00135
GBMASF1A →+0.392+0.353<.001.00434
LSCCREPS1 →+0.293+0.541<.001<.00134
GBMRNGTT →+0.428+0.456<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,319 associations by consensus.

LYRM2 vs AFDN — BRCA

Per-sample scatter of LYRM2 vs AFDN in BRCA (Pearson r = 0.32).

Explore this scatter interactively →

Exploration