LYRM2

Across TCGA patient cohorts, LYRM2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYRM2-associated genes across cancer lineages are MIR551A and SETP15. Each is linked with LYRM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYRM2-to-partner and partner-to-LYRM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR551A grouped by LYRM2-low versus LYRM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM2→partner) and Y-score (partner→LYRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR551A →	+0.766	+5.420	<.001	.005	3	1
UCEC	SETP15 →	+0.614	+5.484	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MIR551A by LYRM2 expression — UCEC

Explore this box plot interactively →