LYRM2

Across TCGA cell cohorts, LYRM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,937 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LYRM2-associated GO terms across cancer lineages are 7-methylguanosine mRNA capping, 7-methylguanosine RNA capping, and Negative regulation of nuclear division. Each is linked with LYRM2 in more than 16 cancer types. Because this analysis shows association rather than direction, both LYRM2-to-partner and partner-to-LYRM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine mRNA capping grouped by LYRM2-low versus LYRM2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYRM2→partner) and Y-score (partner→LYRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	7-methylguanosine mRNA capping →	+0.118	+0.814	<.001	.004	3	17
LUNG_NSCLC_LUSC	7-methylguanosine RNA capping →	+0.118	+0.814	<.001	.004	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.140	+1.003	<.001	.001	3	15
KIDNEY	Negative regulation of mitotic nuclear division →	+0.126	+1.015	<.001	<.001	3	15
SKIN	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.104	+0.475	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.135	+0.849	.002	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,937 associations by consensus.

7-methylguanosine mRNA capping by LYRM2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →