LYPLAL1

Across TCGA patient cohorts, LYPLAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,399 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYPLAL1-associated proteins across cancer lineages are RCOR3, RPRD2, and NUCKS1. Each is linked with LYPLAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYPLAL1-to-partner and partner-to-LYPLAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYPLAL1 versus RCOR3 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPLAL1→partner) and Y-score (partner→LYPLAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCOR3 →	+0.534	+0.994	<.001	<.001	3	5
LUAD	RPRD2 →	+0.309	+0.476	<.001	<.001	3	5
BRCA	NUCKS1 →	+0.707	+0.454	<.001	<.001	3	4
LUAD	NUCKS1_S19 →	+0.477	+0.395	<.001	.002	3	4
HNSC	PRUNE1 →	+0.366	+1.097	<.001	<.001	3	4
GBM	RAC2 →	-0.630	-0.367	.002	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,399 associations by consensus.

LYPLAL1 vs RCOR3 — LSCC

Explore this scatter interactively →