LYPLA2P2

Across TCGA pan-cancer cohorts, LYPLA2P2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LYPLA2P2 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LYPLA2P2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LYPLA2P2 expression acts as an unfavorable survival marker, although some lineages such as CESC and LUAD show a favorable association.

CESC, LIHC, and LUAD are the cancer types where LYPLA2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Quartile	II,III,IV	0.721	0.267	.003	58	view →
LIHC	DFS	Quartile	All	0.471	0.615	.009	29	view →
LUAD	DFS	Median	IV	0.843	0.240	.001	18	view →
LGG	DFS	Quartile	All	0.615	0.774	<.001	16	view →
UCEC	DFS	Median	IV	0.845	0.539	.025	14	view →
LAML	DFS	Median	All	0.283	0.513	.020	12	view →
READ	OS	Quartile	IV	0.559	1.000	.021	9	view →
SKCM	OS	Quartile	III,IV	0.940	0.713	.011	8	view →
COAD	OS	Tertile	IV	0.349	0.855	.008	8	view →
LUSC	DFS	Quartile	All	0.832	0.695	.022	8	view →
HNSC	OS	Median	III,IV	0.574	0.746	.017	7	view →
UCS	OS	Quartile	All	0.521	0.775	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

LYPLA2P2–CESC (DFS)

Open the CESC breakdown →