LYPD8

Across TCGA patient cohorts, LYPD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,973 significant associations in total. LGG shows the largest number of these associations.

The most reproducible LYPD8-associated GO terms across cancer lineages are Reticulophagy, Receptor metabolic process, and Protein K11-linked ubiquitination. Each is linked with LYPD8 in more than 10 cancer types. Because this analysis shows association rather than direction, both LYPD8-to-partner and partner-to-LYPD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reticulophagy grouped by LYPD8-low versus LYPD8-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD8→partner) and Y-score (partner→LYPD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Reticulophagy →	+0.051	+1.074	.002	.002	3	10
GBM	Receptor metabolic process →	+0.037	+0.390	<.001	<.001	2	11
ESCA	Protein K11-linked ubiquitination →	+0.035	+0.749	.002	<.001	3	9
LUSC	Regulation of inclusion body assembly →	+0.039	+0.475	<.001	<.001	3	9
ESCA	Nucleoside bisphosphate metabolic process →	+0.036	+1.001	.001	<.001	3	9
GBM	Organelle fusion →	+0.027	+0.502	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,973 associations by consensus.

Reticulophagy by LYPD8 expression — ESCA

Explore this box plot interactively →