LYPD6B

Across TCGA patient cohorts, LYPD6B protein abundance is significantly associated with the RNA expression of many other genes, with 647 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LYPD6B-associated genes across cancer lineages are BIK, DDHD1, and ADNP2. Each is linked with LYPD6B in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD6B-to-partner and partner-to-LYPD6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYPD6B versus BIK in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD6B→partner) and Y-score (partner→LYPD6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BIK →	+1.098	+1.741	<.001	.002	3	1
UCEC	DDHD1 →	-0.485	-1.757	.005	.001	3	1
UCEC	ADNP2 →	-0.463	-2.030	.004	.001	3	1
UCEC	GABRE →	+1.513	+1.699	.003	.002	3	1
UCEC	EZH2 →	-0.928	-2.193	.003	<.001	3	1
UCEC	APBA1 →	+0.803	+1.868	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 647 associations by consensus.

LYPD6B vs BIK — UCEC

Explore this scatter interactively →