LYPD6B

Across TCGA cell cohorts, LYPD6B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,317 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LYPD6B-associated GO terms across cancer lineages are Negative regulation of response to endoplasmic reticulum stress, Response to topologically incorrect protein, and Response to unfolded protein. Each is linked with LYPD6B in more than 9 cancer types. Because this analysis shows association rather than direction, both LYPD6B-to-partner and partner-to-LYPD6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to endoplasmic reticulum stress grouped by LYPD6B-low versus LYPD6B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD6B→partner) and Y-score (partner→LYPD6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of response to endoplasmic reticulum stress →	+0.093	+2.143	.005	.005	3	10
PANCREAS	Response to topologically incorrect protein →	+0.091	+2.064	.002	.008	3	9
OVARY	Response to unfolded protein →	+0.080	+2.501	<.001	.006	3	8
PANCREAS	Establishment of protein localization to endoplasmic reticulum →	+0.074	+1.892	.003	.001	3	8
PANCREAS	Regulation of response to endoplasmic reticulum stress →	+0.088	+2.395	.001	<.001	3	8
OVARY	Purine nucleoside triphosphate biosynthetic process →	+0.065	+2.209	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,317 associations by consensus.

Negative regulation of response to endoplasmic reticulum stress by LYPD6B expression — URINARY_TRACT

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