LYPD5

Across TCGA cell cohorts, LYPD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,033 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LYPD5-associated GO terms across cancer lineages are Protein stabilization, Membrane raft assembly, and Regulation of cytokine-mediated signaling pathway. Each is linked with LYPD5 in more than 11 cancer types. Because this analysis shows association rather than direction, both LYPD5-to-partner and partner-to-LYPD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by LYPD5-low versus LYPD5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD5→partner) and Y-score (partner→LYPD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein stabilization →	+0.068	+0.938	<.001	<.001	2	12
PANCREAS	Membrane raft assembly →	+0.138	+0.906	.001	<.001	3	11
SOFT_TISSUE	Regulation of cytokine-mediated signaling pathway →	+0.065	+0.379	<.001	.003	3	11
LIVER	Positive regulation of purine nucleotide biosynthetic process →	+0.187	+0.169	<.001	.002	3	10
LIVER	Positive regulation of ATP biosynthetic process →	+0.186	+0.174	<.001	.002	3	10
LIVER	Positive regulation of nucleotide biosynthetic process →	+0.187	+0.169	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,033 associations by consensus.

Protein stabilization by LYPD5 expression — OVARY

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