LYPD4

Across TCGA patient cohorts, LYPD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,683 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LYPD4-associated GO terms across cancer lineages are Negative regulation of mRNA processing, rRNA methylation, and Mitochondrial translation. Each is linked with LYPD4 in more than 16 cancer types. Because this analysis shows association rather than direction, both LYPD4-to-partner and partner-to-LYPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA processing grouped by LYPD4-low versus LYPD4-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD4→partner) and Y-score (partner→LYPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of mRNA processing →	+0.079	+0.218	<.001	.002	3	17
STAD	rRNA methylation →	+0.052	+0.268	<.001	<.001	3	15
STAD	Mitochondrial translation →	+0.081	+0.289	<.001	<.001	3	15
ESCA	Mitochondrial respiratory chain complex assembly →	+0.089	+0.328	<.001	<.001	3	15
STAD	Nucleoside phosphate biosynthetic process →	+0.063	+0.296	<.001	<.001	3	15
ESCA	Regulation of double-strand break repair via nonhomologous end joining →	+0.058	+0.271	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,683 associations by consensus.

Negative regulation of mRNA processing by LYPD4 expression — ESCA

Explore this box plot interactively →