LYPD4

Across TCGA cell cohorts, LYPD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 127 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LYPD4-associated GO terms across cancer lineages are Regulation of platelet-derived growth factor receptor-beta signaling pathway, Eosinophil mediated immunity, and Regulation of protein autophosphorylation. Each is linked with LYPD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD4-to-partner and partner-to-LYPD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of platelet-derived growth factor receptor-beta signaling pathway grouped by LYPD4-low versus LYPD4-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD4→partner) and Y-score (partner→LYPD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of platelet-derived growth factor receptor-beta signaling pathway →	+0.088	+0.028	.005	.002	3	2
LARGE_INTESTINE	Eosinophil mediated immunity →	+0.104	+0.027	.004	.004	3	2
LARGE_INTESTINE	Regulation of protein autophosphorylation →	+0.140	+0.025	.003	.006	3	2
LARGE_INTESTINE	Positive regulation of protein autophosphorylation →	+0.169	+0.025	.006	.008	3	2
BREAST	Apoptotic DNA fragmentation →	-0.086	-0.047	.001	.005	3	2
BREAST	Branched-chain amino acid catabolic process →	+0.074	+0.033	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

Regulation of platelet-derived growth factor receptor-beta signaling pathway by LYPD4 expression — LARGE_INTESTINE

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