LYPD3

Across TCGA cell cohorts, LYPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,082 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible LYPD3-associated GO terms across cancer lineages are Response to indole-3-methanol, Epidermal growth factor receptor signaling pathway, and Rho protein signal transduction. Each is linked with LYPD3 in more than 10 cancer types. Because this analysis shows association rather than direction, both LYPD3-to-partner and partner-to-LYPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by LYPD3-low versus LYPD3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD3→partner) and Y-score (partner→LYPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to indole-3-methanol →	+0.243	+3.239	<.001	<.001	3	11
STOMACH	Epidermal growth factor receptor signaling pathway →	+0.095	+2.311	.005	.003	3	11
OESOPHAGUS	Rho protein signal transduction →	+0.154	+2.767	.003	.006	3	10
URINARY_TRACT	NMDA selective glutamate receptor signaling pathway →	+0.248	+3.467	<.001	<.001	3	10
STOMACH	Regulation of fat cell differentiation →	+0.074	+3.020	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of protein-containing complex assembly →	+0.068	+3.204	.003	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,082 associations by consensus.

Response to indole-3-methanol by LYPD3 expression — STOMACH

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