Across TCGA patient cohorts, LYPD2 protein abundance is significantly associated with the RNA expression of many other genes, with 610 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LYPD2-associated genes across cancer lineages are RPTN, OR5BD1P, and CAT. Each is linked with LYPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD2-to-partner and partner-to-LYPD2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD2→partner) and Y-score (partner→LYPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPTN →	+1.776	+0.915	.001	<.001	3	2
HNSC	OR5BD1P →	+0.559	+1.175	.009	<.001	3	2
OV	CAT →	-0.885	-1.804	.004	.004	3	1
OV	IL6ST →	-0.860	-2.364	.003	.005	3	1
OV	SCYL2 →	-0.487	-2.482	<.001	.001	3	1
OV	CERS3 →	+0.655	+2.405	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 610 associations by consensus.

Exploration

LYPD2 survival (RNA) · tumor vs normal (RNA) · all LYPD2 data types