Across TCGA cell cohorts, LYPD2 mutation is significantly associated with the mutation status of many other genes, with 1,891 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LYPD2-associated genes across cancer lineages are PRKCA, BTG3, and PBRM1. Each is linked with LYPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYPD2-to-partner and partner-to-LYPD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD2→partner) and Y-score (partner→LYPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRKCA →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	BTG3 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	PBRM1 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	RAD54L2 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	PCF11 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	PASD1 →	+6.321	+6.321	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,891 associations by consensus.

Exploration

LYPD2 survival (RNA) · tumor vs normal (RNA) · all LYPD2 data types