LYPD1

Across TCGA patient cohorts, LYPD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYPD1-associated proteins across cancer lineages are ITGAV, SERPINB8, and MPC2. Each is linked with LYPD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LYPD1-to-partner and partner-to-LYPD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYPD1 versus ITGAV in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD1→partner) and Y-score (partner→LYPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGAV →	+0.438	+0.827	<.001	.002	3	4
UCEC	SERPINB8 →	+0.466	+1.160	<.001	<.001	3	3
UCEC	MPC2 →	-0.382	-0.821	.001	.005	3	3
LUAD	PRRC2A_T1347 →	+0.636	+0.578	.001	.002	3	3
LUAD	NAMPT →	+0.714	+0.752	.001	<.001	3	3
PDAC	NIPSNAP1 →	-0.302	-0.372	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,098 associations by consensus.

LYPD1 vs ITGAV — GBM

Explore this scatter interactively →