LYPD1

Across TCGA cell cohorts, LYPD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,316 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LYPD1-associated GO terms across cancer lineages are T cell homeostasis, Integrin-mediated signaling pathway, and Cellular response to environmental stimulus. Each is linked with LYPD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both LYPD1-to-partner and partner-to-LYPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell homeostasis grouped by LYPD1-low versus LYPD1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYPD1→partner) and Y-score (partner→LYPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	T cell homeostasis →	+0.124	+1.989	<.001	<.001	3	12
LIVER	Integrin-mediated signaling pathway →	+0.128	+3.064	.005	.003	3	10
SOFT_TISSUE	Cellular response to environmental stimulus →	+0.039	+2.052	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Negative regulation of molecular function →	+0.055	+1.558	<.001	<.001	3	10
SOFT_TISSUE	Cellular response to abiotic stimulus →	+0.039	+2.052	<.001	<.001	3	10
SKIN	Regulation of intracellular transport →	+0.047	+1.928	.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,316 associations by consensus.

T cell homeostasis by LYPD1 expression — URINARY_TRACT

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