LYNX1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LYNX1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,003 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LYNX1-associated genes across cancer lineages are RIMS2, RNU6-529P, and FRMPD4-AS1. Each is linked with LYNX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYNX1-to-partner and partner-to-LYNX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYNX1 versus RIMS2 in GBM, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYNX1→partner) and Y-score (partner→LYNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRIMS2 →+1.271+0.925<.001<.00132
LUADRNU6-529P →+1.304+0.592<.001<.00132
GBMFRMPD4-AS1 →+0.669+0.745<.001<.00132
LUADSLC22A17 →+1.155+0.857.005<.00132
LUADMEFV →-0.808-0.971<.001<.00131
LUADSLC4A3 →+0.900+0.539.002.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,003 associations by consensus.

LYNX1 vs RIMS2 — GBM

Per-sample scatter of LYNX1 vs RIMS2 in GBM (Pearson r = 0.39).

Explore this scatter interactively →

Exploration