LYNX1

Across TCGA cell cohorts, LYNX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,547 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LYNX1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with LYNX1 in more than 13 cancer types. Because this analysis shows association rather than direction, both LYNX1-to-partner and partner-to-LYNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by LYNX1-low versus LYNX1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYNX1→partner) and Y-score (partner→LYNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of myoblast fusion →	+0.097	+1.561	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.099	+1.561	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.083	+0.697	.004	.008	3	11
CNS	Electron transport chain →	+0.070	+1.721	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of syncytium formation by plasma membrane fusion →	+0.086	+1.561	<.001	<.001	3	11
OVARY	Lysosomal lumen acidification →	+0.110	+1.262	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,547 associations by consensus.

Negative regulation of myoblast fusion by LYNX1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →