LYNX1

Across TCGA cell cohorts, LYNX1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LYNX1-associated genes across cancer lineages are OR4F4 and OR9I1. Each is linked with LYNX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYNX1-to-partner and partner-to-LYNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F4 grouped by LYNX1-low versus LYNX1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYNX1→partner) and Y-score (partner→LYNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.020	+4.273	<.001	.006	3	1
BLOOD_Lymphoma	OR9I1 →	+0.110	+4.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR4F4 by LYNX1 expression — LARGE_INTESTINE

Explore this box plot interactively →