LYL1

Across TCGA patient cohorts, LYL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,495 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LYL1-associated proteins across cancer lineages are WIPF1, RCSD1, and AIF1. Each is linked with LYL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LYL1-to-partner and partner-to-LYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYL1 versus WIPF1 in OV, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYL1→partner) and Y-score (partner→LYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.506	+0.692	<.001	<.001	3	10
OV	RCSD1 →	+0.524	+0.584	<.001	<.001	3	10
GBM	AIF1 →	+0.799	+0.761	<.001	<.001	3	10
HNSC	FNBP1 →	+0.417	+0.760	<.001	<.001	3	10
GBM	GPSM3 →	+0.453	+0.632	<.001	<.001	3	10
OV	IL16 →	+0.613	+0.806	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,495 associations by consensus.

LYL1 vs WIPF1 — OV

Explore this scatter interactively →