LYL1

Across TCGA patient cohorts, LYL1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,501 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LYL1-associated genes across cancer lineages are BCL2A1, FCGR3B, and CXCL8. Each is linked with LYL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LYL1-to-partner and partner-to-LYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYL1 versus BCL2A1 in HNSC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYL1→partner) and Y-score (partner→LYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BCL2A1 →	-1.546	-0.913	<.001	<.001	3	5
UCEC	FCGR3B →	-1.523	-0.993	<.001	<.001	3	5
GBM	CXCL8 →	-2.069	-0.618	<.001	<.001	3	5
PDAC	CXCR2 →	-1.156	-0.945	.001	.001	3	5
UCEC	MEFV →	-0.752	-0.792	<.001	<.001	3	4
UCEC	CSF3R →	-1.104	-0.786	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,501 associations by consensus.

LYL1 vs BCL2A1 — HNSC

Explore this scatter interactively →