LYL1

Across TCGA cell cohorts, LYL1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,703 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LYL1-associated genes across cancer lineages are LIMD2, SLC16A3, and VAT1. Each is linked with LYL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LYL1-to-partner and partner-to-LYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYL1 versus LIMD2 in URINARY_TRACT, with a Pearson correlation of 0.74.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYL1→partner) and Y-score (partner→LYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	LIMD2 →	+2.372	+0.896	<.001	<.001	3	6
LARGE_INTESTINE	SLC16A3 →	+3.034	+0.587	<.001	<.001	3	6
LARGE_INTESTINE	VAT1 →	+1.512	+0.567	<.001	<.001	3	5
BLOOD_Leukemia	THEMIS2 →	+1.337	+1.614	<.001	<.001	3	5
LUNG_NSCLC_LUSC	SLC43A3 →	+4.226	+1.278	.001	.001	2	6
LUNG_NSCLC_LUSC	EVA1B →	+1.784	+1.093	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,703 associations by consensus.

LYL1 vs LIMD2 — URINARY_TRACT

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