LYL1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LYL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,204 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LYL1-associated GO terms across cancer lineages are Blood vessel maturation, Viral process, and Protein depolymerization. Each is linked with LYL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LYL1-to-partner and partner-to-LYL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood vessel maturation grouped by LYL1-low versus LYL1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LYL1→partner) and Y-score (partner→LYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASBlood vessel maturation →-0.460-0.701.004<.001310
LARGE_INTESTINEViral process →+0.048+0.393<.001.00338
LARGE_INTESTINEProtein depolymerization →+0.089+0.402<.001.00237
OESOPHAGUSRegulation of metallopeptidase activity →+0.197+0.465<.001<.00137
KIDNEYRegulation of plasma lipoprotein particle levels →+0.095+0.360.008.00637
BLOOD_LymphomaMicroglia development →-0.499-1.377.007.00437
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,204 associations by consensus.

Blood vessel maturation by LYL1 expression — PANCREAS

Box plot of Blood vessel maturation in LYL1-low vs LYL1-high samples in PANCREAS.

Explore this box plot interactively →

Exploration