LYG1

Across TCGA patient cohorts, LYG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,670 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LYG1-associated proteins across cancer lineages are PARP1, PAXBP1, and PLS3. Each is linked with LYG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LYG1-to-partner and partner-to-LYG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LYG1 versus PARP1 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LYG1→partner) and Y-score (partner→LYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARP1 →	+0.535	+0.847	<.001	<.001	3	4
LSCC	PAXBP1 →	+0.202	+0.553	.004	<.001	3	4
GBM	PLS3 →	-0.501	-0.472	<.001	<.001	3	4
COAD	UHRF1 →	+0.590	+0.978	<.001	<.001	3	4
GBM	PYGL →	-0.616	-0.567	<.001	<.001	3	3
HNSC	MYEF2 →	+0.848	+0.795	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,670 associations by consensus.

LYG1 vs PARP1 — HNSC

Explore this scatter interactively →