LYG1

Across TCGA patient cohorts, LYG1 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LYG1-associated genes across cancer lineages are PDK1_pS241. Each is linked with LYG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYG1-to-partner and partner-to-LYG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDK1_pS241 grouped by LYG1-low versus LYG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYG1→partner) and Y-score (partner→LYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDK1_pS241 →	+0.250	+2.820	.016	.036	1	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PDK1_pS241 by LYG1 expression — UCEC

Explore this box plot interactively →