LY96

Across TCGA patient cohorts, LY96 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LY96-associated genes across cancer lineages are ASNS, INPP4B, and Smad1. Each is linked with LY96 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY96-to-partner and partner-to-LY96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by LY96-low versus LY96-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY96→partner) and Y-score (partner→LY96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.552	+2.321	.002	.035	3	2
SKCM	INPP4B →	-0.248	-2.982	.024	.036	1	1
SKCM	Smad1 →	-0.171	-3.000	.039	.036	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ASNS by LY96 expression — UCEC

Explore this box plot interactively →