LY96

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LY96 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LY96-associated genes across cancer lineages are SIGLECL1. Each is linked with LY96 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY96-to-partner and partner-to-LY96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLECL1 grouped by LY96-low versus LY96-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY96→partner) and Y-score (partner→LY96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESIGLECL1 →+0.022+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SIGLECL1 by LY96 expression — LARGE_INTESTINE

Box plot of SIGLECL1 in LY96-low vs LY96-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration