LY9

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LY9 protein abundance is significantly associated with the RNA expression of many other genes, with 5,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LY9-associated genes across cancer lineages are THADA, C2orf49, and ABCG5. Each is linked with LY9 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY9-to-partner and partner-to-LY9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LY9 versus THADA in LSCC, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY9→partner) and Y-score (partner→LY9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTHADA →-0.567-0.652<.001<.00132
LSCCC2orf49 →-0.549-0.705.001.00132
LSCCABCG5 →-0.331-0.564<.001<.00132
LUADSLC39A4 →-0.839-0.309.007.00332
LSCCRPS7P10 →-0.602-0.676.001.00132
LSCCRN7SL531P →-0.656-0.610<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,595 associations by consensus.

LY9 vs THADA — LSCC

Per-sample scatter of LY9 vs THADA in LSCC (Pearson r = -0.56).

Explore this scatter interactively →

Exploration