LY9

Across TCGA cell cohorts, LY9 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LY9-associated genes across cancer lineages are OR51J1, USP29, and SPHKAP. Each is linked with LY9 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY9-to-partner and partner-to-LY9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51J1 grouped by LY9-low versus LY9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY9→partner) and Y-score (partner→LY9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR51J1 →	+0.143	+4.191	<.001	.007	3	2
URINARY_TRACT	USP29 →	+0.033	+5.087	<.001	.004	3	1
URINARY_TRACT	SPHKAP →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	SPZ1 →	+0.056	+5.087	<.001	.004	3	1
URINARY_TRACT	AHSP →	+0.096	+5.087	<.001	.004	3	1
URINARY_TRACT	LEUTX →	+0.046	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR51J1 by LY9 expression — BLOOD_Lymphoma

Explore this box plot interactively →