LY86

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LY86 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,931 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LY86-associated proteins across cancer lineages are WAS, WIPF1, and SASH3. Each is linked with LY86 in more than 9 cancer types. Because this analysis shows association rather than direction, both LY86-to-partner and partner-to-LY86 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LY86 versus WAS in GBM, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LY86→partner) and Y-score (partner→LY86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWAS →+0.648+1.130<.001<.001310
OVWIPF1 →+0.490+0.975<.001<.001310
OVSASH3 →+0.701+1.471<.001<.001310
GBMHCLS1 →+0.820+1.265<.001<.001310
GBMIFI30 →+0.830+1.001<.001<.001310
OVANKRD44 →+0.464+0.866<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,931 associations by consensus.

LY86 vs WAS — GBM

Per-sample scatter of LY86 vs WAS in GBM (Pearson r = 0.72).

Explore this scatter interactively →

Exploration