LY86

Across TCGA patient cohorts, LY86 mutation is significantly associated with the RNA expression of many other genes, with 342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LY86-associated genes across cancer lineages are RNA5SP65, TRIM39-RPP21, and OR7E125P. Each is linked with LY86 in more than 1 cancer types. Because this analysis shows association rather than direction, both LY86-to-partner and partner-to-LY86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP65 grouped by LY86-low versus LY86-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY86→partner) and Y-score (partner→LY86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP65 →	+0.745	+4.888	<.001	.005	3	2
UCEC	TRIM39-RPP21 →	+0.122	+3.133	<.001	.002	3	2
BRCA	OR7E125P →	+0.026	+8.057	<.001	.005	3	1
BRCA	RNA5SP335 →	+0.419	+5.230	<.001	.007	3	1
BRCA	LINC00474 →	+0.121	+5.409	<.001	.005	3	1
BRCA	MIR147A →	+0.566	+4.995	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 342 associations by consensus.

RNA5SP65 by LY86 expression — LUAD

Explore this box plot interactively →