LY6K

Across TCGA patient cohorts, LY6K RNA expression is significantly associated with the go_rna of many other GO terms, with 7,044 significant associations in total. THYM shows the largest number of these associations.

The most reproducible LY6K-associated GO terms across cancer lineages are L-proline biosynthetic process, Binding of sperm to zona pellucida, and Caveola assembly. Each is linked with LY6K in more than 12 cancer types. Because this analysis shows association rather than direction, both LY6K-to-partner and partner-to-LY6K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-proline biosynthetic process grouped by LY6K-low versus LY6K-high in SARC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6K→partner) and Y-score (partner→LY6K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	L-proline biosynthetic process →	+0.064	+0.931	<.001	.001	3	13
UCS	Binding of sperm to zona pellucida →	-0.068	-1.229	<.001	<.001	3	12
THYM	Caveola assembly →	+0.081	+1.702	<.001	<.001	3	11
UCS	Sperm-egg recognition →	-0.068	-1.250	<.001	<.001	3	10
ESCA	Proline metabolic process →	+0.052	+1.050	<.001	<.001	3	10
STAD	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.047	+0.622	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,044 associations by consensus.

L-proline biosynthetic process by LY6K expression — SARC

Explore this box plot interactively →