LY6K

Across TCGA cell cohorts, LY6K RNA expression is significantly associated with the go_rna of many other GO terms, with 3,964 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LY6K-associated GO terms across cancer lineages are Cellular response to platelet-derived growth factor stimulus, Response to temperature stimulus, and Positive regulation of calcium ion transport into cytosol. Each is linked with LY6K in more than 9 cancer types. Because this analysis shows association rather than direction, both LY6K-to-partner and partner-to-LY6K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to platelet-derived growth factor stimulus grouped by LY6K-low versus LY6K-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6K→partner) and Y-score (partner→LY6K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular response to platelet-derived growth factor stimulus →	+0.144	+1.893	.001	.005	3	10
SOFT_TISSUE	Response to temperature stimulus →	+0.041	+1.394	.001	.006	3	9
SOFT_TISSUE	Positive regulation of calcium ion transport into cytosol →	+0.270	+2.234	<.001	<.001	3	9
BONE	Regulation of BMP signaling pathway →	+0.106	+3.037	<.001	.002	2	9
BONE	Regulation of stem cell proliferation →	+0.129	+2.991	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of syncytium formation by plasma membrane fusion →	+0.203	+2.721	.006	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,964 associations by consensus.

Cellular response to platelet-derived growth factor stimulus by LY6K expression — LUNG_SCLC

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