Across TCGA pan-cancer cohorts, LY6G6F RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LY6G6F data layer compared with 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LY6G6F RNA is associated with better overall survival. In most high-consensus cancer types, elevated LY6G6F expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, CESC, and COAD are the cancer types where LY6G6F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.853	0.730	.001	71	view →
CESC	DFS	Median	All	0.829	0.682	.002	52	view →
COAD	DFS	Tertile	All	0.597	0.843	<.001	47	view →
READ	DFS	Median	IV	0.354	0.790	.002	33	view →
LUSC	DFS	Quartile	II,III,IV	0.524	0.310	.003	31	view →
SCLC	DFS	Quartile	II,III,IV	0.825	0.456	.010	29	view →
THCA	DFS	Tertile	All	0.979	0.926	.003	27	view →
LAML	DFS	Tertile	All	0.259	0.531	.005	22	view →
PAAD	OS	Tertile	II,III,IV	0.300	0.529	.033	18	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	18	view →
LGG	OS	Tertile	All	0.801	0.908	.008	9	view →
UCEC	OS	Median	II,III,IV	0.886	0.824	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration

Same gene, other analysis: LY6G6F tumor-vs-normal RNA expression · all LY6G6F data types