LY6G5B

Across TCGA cell cohorts, LY6G5B mutation is significantly associated with the mutation status of many other genes, with 844 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LY6G5B-associated genes across cancer lineages are TWF2, GPR162, and ZNF285. Each is linked with LY6G5B in more than 1 cancer types. Because this analysis shows association rather than direction, both LY6G5B-to-partner and partner-to-LY6G5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TWF2 grouped by LY6G5B-low versus LY6G5B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LY6G5B→partner) and Y-score (partner→LY6G5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TWF2 →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	GPR162 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	ZNF285 →	+6.321	+6.321	.001	.001	1	2
LARGE_INTESTINE	CRKL →	+5.523	+5.523	.003	.003	1	2
BLOOD_Leukemia	UBP1 →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	JPH3 →	+4.000	+5.050	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 844 associations by consensus.

TWF2 by LY6G5B expression — BLOOD_Leukemia

Explore this box plot interactively →