LUZP4

Across TCGA cell cohorts, LUZP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 258 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LUZP4-associated GO terms across cancer lineages are Negative regulation of bicellular tight junction assembly, Cellular response to glucose starvation, and Negative regulation of trophoblast cell migration. Each is linked with LUZP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both LUZP4-to-partner and partner-to-LUZP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of bicellular tight junction assembly grouped by LUZP4-low versus LUZP4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LUZP4→partner) and Y-score (partner→LUZP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of bicellular tight junction assembly →	-0.111	-0.034	<.001	<.001	3	3
BLOOD_Lymphoma	Cellular response to glucose starvation →	+0.059	+0.044	<.001	.005	3	3
OVARY	Negative regulation of trophoblast cell migration →	-0.178	-0.028	<.001	.004	3	2
OVARY	Negative regulation of oligodendrocyte differentiation →	+0.093	+0.022	.006	.002	3	2
OVARY	Negative regulation of glial cell proliferation →	+0.112	+0.031	<.001	.002	3	2
LARGE_INTESTINE	Regulation of pigmentation →	+0.061	+0.005	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 258 associations by consensus.

Negative regulation of bicellular tight junction assembly by LUZP4 expression — OVARY

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